How to Getting ?

From Terminal de Buses Quitumbe (south of Quito), take one of the several buses that leave to Machachi. There are only two bus companies that offer their service to Machachi, Transportes Mejia (green) and Carlos Brito (purple). 
Also you can fine the bus in Trebol this is near the  Mariscal (tourist Place in Quito)  You'll need to get off the bus at Mercado Central de Machachi.

Once in Machachi, take another bus to the town of El Chaupi (blue-and-white buses signed “El Chaupi”). They leave every 30 minutes from the Market’s corner. The best spot to catch a ride is at “Supermercados TIA”.
The statue of a woman milking a cow will let you know that you've arrived to El Chaupi (13 Km-bus-ride on a cobbled road, well actually half of it has been paved). In Chaupi we have our oficce informatión this is close to the central park of CHaupi. You can easily see our sign . From El Chaupi continue on a very well signed road towards the Illinizas parking lot at 3,900 m. (La Virgen, there's a small shrine to the virgin) which is about 9 km away. 

From La Virgen Parking Lot (3,900 m / 12,792) follow the well-marked and signed trail that ends up at the northern moraine ridge of Illiniza Sur, 2 hours after leaving from the trailhead. Another trail continues up switch backing by the steep/sharp scree ridge. 

Follow this ridge up for about 30 minutes - 45 minutes until the trail splits to the right (west) taking you to the Nuevos Horizontes refuge which is clearly visible from the upper part of the ridge.

Private transportation:

Transportation to La Virgen Parking Lot can be arranged at Refugio Los Illinizas Office located at the north side of the park in the town of El Chaupi or in La Llovizna Lodge. Their rates are USD. 15.00 one way (40 minute-ride).

Transportation from Machachi , their rates are about USD. 25.00 .

Transportation from Quito can be arranged in travel agencies for USD. 80,00 per day.

Public transportation:

Transportes Mejia and Carlos Brito leave every 20 minutes to Machachi from Terminal Quitumbe in Quito (USD. 0.75 , 1 hour).

Transportes El Chaupi leave every 30 minutes from Machachi to El Chaupi (USD. 0.35, 40 minutes).